Zymogen Forte

Drugs , Gastrointestinal System / October 8, 2016

Class: Gastrointestinal System
Dosage Form: Tablets
Description: Digestive enzymes combination with antiflatulent agent
Stock: Available
Manufacturer: Nile Co. Pharma

Composition:

Each tablet contains:
Pepsin……………………………………..100 mg
Amylase………………………5000 (NF Units)
Protease……………………..5000 (NF Units)
Lipase…………………………..800 (NF Units)
Ox bile……………………………………….20 mg
Hemicellulase…………………………….40 mg
Dimethylpolysiloxane………………….25 mg

Properties:

Digestive enzymes are of definite value in clinical management of various dyspepsias. Enzymes included in Zymogen Forte are combined in order to replace deficient secretions in the gastrointestinal tract. Zymogen Forte tablets are prepared in the form of two layers. The outer layer contains pepsin, dimethylpolysiloxane and vitamin B1.
Pepsin is a proteolytic enzyme which is active in acid media. It controls the degradation of proteins Into proteoses and peptones. Dimethylpolysiloxane exerts a defoaming effect, it is used in the treatment of flatulence for the elimination of gas or foam from the gastrointestinal tract.
Vitamin B1 improves appetite and gastrointestinal motility. The inner layer is enteric coated to protect the pancreatic enzymes against inactivation by gastric juice. The enteric coat disintegrates in the intestine where the enzymes liberated exercise their action on the digestion of fats, proteins and carbohydrates. Ox bile promotes the enzymatic splitting of fats by emulsifying the neutral fats and activating the lipase. lt stimulates intestinal peristalsis in chronic constipation.
Hemicellulase brings about an early breakdown of cellulose, thus reducing the amount of substrate available for bacterial fermentative gas formation.

Indications:

Zymogen Forte is indicated in:

  • Dyspepsias due to gastric pancreatic, biliary and intestinal dysfunction
  • Relief of abdominal distension

Dosage and Administration:

One tablet three times daily during or after the meal.

Packaging:

Pack of 2 strips of 10 tablets each.

Storage:

Store at room temperature, below 25°C.

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