Class: Central Nervous System
Dosage Form: Tablets
Description: Anxiolytic and hypnotic
Stock: Out of Stock
Oxazepam is a benzodiazepine which exerts its pharmacological effect at the site of the GABA synapse increasing the affinity of the receptor for GABA thus reducing GABA turnover, which is a major inhibitory transmitter in the CNS.
Oxazacin is indicated in:
- Oxazepam is used in management of anxiety or for the short-term relief of the symptoms of anxiety
- Anxiety, tension, agitation, and irritability in older patients
- Anxiety associated with depression.
Oxazacin is contraindicated in:
- Hypersensitivity to oxazepam
- Oxazepam is contraindicated in psychoses
- Oxazepam is contraindicated during pregnancy or lactation
- Not indicated for pediatric use
Alcohol or other CNS depressant drugs may increase the effect of oxazepam.
The following side effects are to be noted:
- Mild drowsiness is commonly seen in the first few days of therapy
- Rare instances of minor diffuse skin rashes, urticaria, nausea, edema, slurred speech, tremors and altered libido
- Mild paradoxical reactions have occurred
- Such side effects have been infrequent and are generally controlled with reduction of dosage
Dosage and Administration:
The following dosage is generally recommended:
- Mild to moderate anxiety with associated tension, irritability, agitation, or related symptoms of functional origin or secondary to organic disease: 10 to 15 mg 3 or 4 times daily
- Severe anxiety syndromes, agitation, or anxiety associated with depression: 15 to 30 mg 3 or 4 times daily
- Older patients with anxiety, tension, irritability and agitation: initial dose 10 mg 3 times daily, to be increased, if necessary, according to physician’s directions up to 15 mg 3 or 4 times daily
- Alcoholics with acute inebriation, tremulousness or anxiety on withdrawal:15 to 30 mg, 3 or 4 times daily
Pregnancy and Lactation:
Oxazepam is contraindicated during pregnancy or lactation.
Patients should avoid driving vehicles or operating machinery because the product may cause drowsiness.
The drug should be withdrawn gradually.
Benzodiazepines may produce psychological & physical dependence, it is advisable that patients consult with their physician before either increasing the dose or abruptly discontinuing the drug.
Periodic blood counts & liver function tests are desirable.
Oxazepam should be administered cautiously to patients whose blood pressure drop may lead to cardiac complication.
Store at room temperature, below 25°C.