Tradename
Nucleo CMP Forte
Generic Name
Cytidine, Uridine
Category
Musculoskeletal System
Form
Capsules
Composition
Cytidine...................5 mg
Uridine................1.33 mg
Description
Properties/Actions
Pharmacology
Nucleo CMP Forte provides the phosphate groups necessary for the union of the monosaccharides with caramins to form the cerebrosides and phosphatidic acids constituting the sphingomyelin and glycerophospholipids, main components of the myelin sheath, thus achieving greater trophic properties for the maturation and axonal regeneration of the nervous tissue.
The acitivity of Nucleo CMP Forte is derived from the incorporation of its active principles in specific metabolic routes.
Nucleo CMP Forte contributes to the groups necessary phosphates for the metabolism of cerebrosides and the sphingomyelin and glycerophospholipids phosphatidic acids that constitute, main components of the myelin sheath, which confers to the product of trophic properties for the maturation and axonal regeneration of the nervous weave.
The experimental tests with animal to which a neuropathy takes place to them have shown that the administration of Nucelo CMP Forte exerts a preventive action and curative. After the administration, it is verified that there is an increase of density of injured nervous fiber, as well as of its diameter, that is to say, increases to its consistency and thickness. This is translated in an activation of the mechanism of axonal regenration and an increase of the speed of the axonal flow. Consequently, the inflammation is diminished, sensitivity is incresaed and the mobilization of affected zone improves.

Pharmacokinetics
The pharmaceutical product is an association of the 2 nucleotides, CMP and UTP. These nucleotides are present in the organism. For this reason it is difficult to make a test of classic pharmacokinetics, administering product and analyzing by means of usual analytical techniques the content in biological liquids, corresponding to the external contribution.
  • Maximum plasma concentration: 20 minutes post-administration by oral route.
  • Average half-life: Oscillates between 1.5 and 5 hours in the alpha phase of distribution; and 8 hours in the beta phase.

UTP is mainly eliminated in the form of uridine, while CMP is eliminated in as cytosine.

Indications
Nucleo CMP Forte is indicatead for the treatment of:
  • Peripheral neuropathies of osteoarticular, metabolic and infectious origins
  • Frigore
  • Neuralgias
Contraindications
Drug Interactions
Side Effects/Adverse Effects
Pregnancy & Lactation
Dosage & Administration
Nucleo CMP Forte capsules are administered vial oral route. The following dosage is generally recommended:
Adults
  • 1-2 capsules, 2 times daily.

Children

  • 1 capsule two times daily, or as prescribed by the physician.
Overdosage
Warnings
Notes
Storage
Store at a temperature not exceeding 30°C, in a dry place.
Packaging
Pack of 1 strips of 10 capsules each.
Manufacturer
Ferrer Internacional
Date Added/Updated
22nd December 2012 7:44 am
//date_format

Miscellaneous

Share This!

Respected Sites

drugs.com

rxlist.com

rxwiki.com

Need Help?

on-call support