Tradename
Flamogen
Generic Name
Bromelain, Trypsin, Rutoside
Category
Topical Preparations
Form
Tablets
Composition
Bromelain..............90 mg
Trypsin..................48 mg
Rutoside..............100 mg
Description
Properties/Actions
Flamogen contains a combination of two proteolytic enzymes (substances which cleave proteins) of plant and animal origin completed with plant flavonoid rutoside that are able to influence efficiently various phases of inflammatory and immune processes.
Components of flamogen remove harmful metabolic products at the site of inflammation and speed up absorption of edemas, bruises, and hematoas. They normalize vessel wall permeability, this reducing edema formation. Flamogen decreases blood viscosity and improves some properties of platelets and erythrocytes participating in thrombi formation. Therefore, Flamogen improves blood circulation in tiny vessels and repairs capillary return of tissue and its nutrient and oxygen supply.
Healing processes and tissue regenration are thus supported and accelerated, and pain associated with inflammation is reduced.
Indications
Flamogen is indicated:
  • In post-traumatic and post-operative edemas.
  • As supportive therapy in the following cases:
    • Inflammatory diseases - Mainly inflammations of urinary and genital organs, veinous inflammations, post-thrombotic syndrome (condition after recurrent inflammations of veins), and crural ulcers.
    • Rheumatic diseases - Rhemuatoid arthritis (inflammatory joint diseases) and verterbral disease.
Contraindications
Known hypersensitivity to bromelain, trypsin or rutoside.
Drug Interactions
Side Effects/Adverse Effects
Flamogen is usually well-tolerated. There were no observed adverse effects during long-term high-dosage administration. Harmless alteration in consistency, color and odor of stool may occur. A sensation of fullnes, flatulence, and occasional episodes of nausea are possible during high-dosage administration. These can be avoided by administration of the enzyme preparation in divided doses during a day. If these symptoms persist, consult your physician.
Allergic reactions (skin rash) may rarely occur and disappear after disocontinuation of the drug. In case of their occurrence, discontinue Flamogen and consult the pyhsician.
Pregnancy & Lactation
Administration of Flamogen during pregnancy and breast-feeding should be consulted with a phyiscian. This also applies to when becoming pregnant during treatment.
Dosage & Administration
Adults
The recommended dose to be used is 6 tablets daily (2x3 or 3x2).
In certain cases such as severe courses of disease, beginning of acute inflammation, post-traumatic and post-operative conditions when a rapid absorption of edema, bruises and hematomas is necessary, it is possible to use 12 tablets daily (4x3 or 3x4) after consulting with a physician.

Children
The recommended dose to be used is 1 tablet per 10 kg of body weight per day. This dosage is to be divided into 2-4 partial doses.

Flamogen should be swallowed on an empty stomach (at least 30 minutes before or 3 hours after meals).
Overdosage
Warnings
Flamogen should be used with caution in patients with severe liver damage and cirrhosis.
The use of Flamogen does not replace antibiotic therapy of infectious inflammation but it does increase its efficacy.
The carbohydrate content of one tablet is equivalent to 4.65 kcal.
Notes
Storage
Store in a cool, dry place, protected from light and at a temperature not exceeding 25°C.
Packaging
Box of 2 blisters of 10 tablets each.
Manufacturer
Sabaa
Price
Date Added/Updated
3rd October 2012 2:10 pm

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