Tradename
Phenadone
Generic Name
Dexamethasone, Chlorpheniramine maleate
Category
Respiratory System
Form
Syrup
Composition
Each 100 ml contains:
Dexamethasone..........................10 mg
Chlorpheniramine maleate............40 mg
Description
Anti-inflammatory and Anti-allergic
Properties/Actions
Phenadone is a combination of well known products:
  • Dexamethasone has a powerful anti-inflammatory and anti-allergic effect.
  • It produces a trivial sodium and water retention. Consequently, drastic salt restriction (to avoid undue sodium retention and hypertension) and administration of potassium salts are not necessary when using Dexamethasone.
  • Under the influence of Dexamethasone inflammatory responses are reduced or abolished. This occurs whether inflammation is induced by infection, chemical agents or trauma.
  • Dexamethasone reduces hyperemia by diminishing the capillary permeability, the local oedema formation, leucocytosis and cellular infiltration.
  • Chlorpheniramine maleate is a potent antihistaminic with a rapid onset of action. It controls allergic coughs and mucosal congestion. Its mild anticholinergic effects help in reducing rhinnorrhea while its sedative action is beneficial to patients with excessive cough.
Indications
In principle Phenadone syrup has the same indication as other adrenocortical hormones, though chiefly in the pediatric field.
  • Bronchial asthma.
  • Urticaria.
  • Other allergic conditions.
  • Acute rheumatic fever and rheumatic arthritis.
Contraindications
  • Absolute: Active and questionably healed tuberculosis.
  • Relative: Peptic ulder, diabetes, osteoperosis and marked emotional instability.
Drug Interactions
Side Effects/Adverse Effects
Pregnancy & Lactation
Dosage & Administration
The dose should be adjusted by the treating physician.
  • Adults: One teaspoonful, 3 times daily.
  • Children: 1/2 teaspoonful, 3 times daily.
  • Infants: 1/4 teaspoonful, 3 times daily.
The dose must be reduced gradually to the minimum effective dose.
Overdosage
Warnings
Notes
Storage
Packaging
Bottles of 100 ml or 125 ml.
Manufacturer
The Arab Drug Company (Egypt)
Date Added/Updated
27th January 2011 1:29pm

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