Curazole

Antifungals , Dermatology , Drugs / October 25, 2016

Class: Topical Preparations
Dosage Form: Cream
Description: Topical antifungal cream
Stock: Available
Manufacturer: Eva Pharma

Composition:

Ketoconazole………………2 g

Properties:

Ketoconazole, is an imidazole derivative with a wide spectrum of activity against pathogenic fungi. It inhibits the biosynthesis of ergosterol, the main sterol of fungal cell membranes, allowing increased permeability and leakage of cellular components.
It has a potent antimycotic activity against dermatophytes such as Microsporum sp. Tri-chophyton sp., Epidermophyton floccosum and against yeast specially Pityrosporum sp.
It also has a rapid symptomatic effect specially on pruritus.

Indications:

Dermatophyte infections of the skin:

  • Tinea corporis
  • Tinea cruris
  • Tinea manus
  • Tinea pedis
  • Tinea versicolor
  • Cutaneous candidiasis
  • Seborrheic dermatitis

Contraindicatons:

Individuals who have shown hypersensitivity to any of Curazole Cream components.

Side Effects:

In very few cases, irritation & burning sensation have been observed.
Individuals who have shown hypersensitivity to any of Curazole Cream components.

Dosage and Administration:

The following is generally recommended:

  • To be applied to the affected area once daily & may be increased to twice in case of seborrheic dermatitis, according to the severity of the case
  • The usual duration of treatment is 2-4 weeks & in case of tinea pedis 4-6 weeks
  • Apply once to twice weekly as a maintenance therapy in seborrheic dermatitis

Warnings:

Curazole cream is not for ophthalmic use.
In case Curazole cream is used immediately after prolonged treatment with topical corticosteroids, irritation may occur, therefore co-treatment is recommended initially and to gradually withdraw the steroid therapy over 2-3 weeks.

Packaging:

Tube of 15 gm cream.

Storage:

Store at room temperature, below 25°C.

No Comments

Leave a Reply

%d bloggers like this:
Skip to toolbar