Cevarol

Drugs , Vitamins and Minerals / November 22, 2016

Class: Vitamins and Minerals
Dosage Form: Tablets
Stock: Available
Manufacturer: Memphis Co.

Composition:

Ascorbic Acid (Vitamin C)………..500 mg

Properties:

Pharmacodynamics
Vitamin C is an essential coenzyme for collagen formation, tissue repair and synthesis of lipids and proteins. It acts both as reducing agent and as an antioxidant. It is necessary for many physiological functions such as metabolism of iron, carbohydrates, tyrosine and folic acid, as well as, resistance to infection, cellular respiration, and preservation of blood vessel integrity. Signs of early vitamin C deficiency include malaise, irritability, hyperkeratosis of hair follicles and bleeding from the nose.

Pharmacokinetics

Vitamin C is normally present in both plasma and red blood cells. The absorbed vitamin is well distributed in the body tissues. Ascorbic acid is excreted by the kidney.

Indications:

Cevarol tablets are indicated in the following cases:

  • Prevention and treatment of scurvy
  • Faulty bone, tooth development, bleeding gums and loosened teeth
  • Cases of increased requirements of vitamin C such as tuberculosis, hyperthyroidism, peptic ulcer, stress, neoplastic disease, pregnancy and lactation, burns and wound healing
  • Patients with infections (rheumatic fever, whooping cough and penumonia)
  • Common cold

Contraindicatons:

It may be contraindicated in persons who have shown hypersensitivity to any component of the preparation.

Drug Interactions:

Large doses of vitamin C interfere with the anticoagulant effect of warfarin.
Concurrent administration of vitamin C will interfere with the effectiveness of disulfiram given to patients to encourage abstinence from alcohol.

Side Effects:

Cevarol tablets are generally well tolerated. Large doses may cause diarrhea.

Dosage and Administration:

The following is generally recommended:

  • In the presence of scurvy: doses of 300 mg to 1 g daily are recommended
  • Wound healing: Doses of 300 to 500 mg daily for a week or 10 days are adequate
  • Severe burns: Daily doses of 200 to 500 mg up to 1 to 2 g are recommended
  • Conditions in which the need for vitamin C is increased: 3 to 5 times the daily optimum allowances appears to be adequate. Daily allowance ranges between 55-60 mg for adults
  • Before operations of gastrectomy: 1 g daily for 4-7 days

Overdosage:

Serious toxicity is very uncommon.
In the event of severe or untoward effects, vitamin C should be terminated pending further evaluation.

Pregnancy and Lactation:

Vitamin C should be given to pregnant women only if clearly needed.
Vitamin C appears in breast milk but may be taken safely during lactation.

Warnings:

Persons with diabetes, those on sodium-restricted diets or anticoagulant therapy, should not take excessive doses of vitamin C.
Acidification of the urine by vitamin C may cause precipitation of oxalate, urate or cystine stones.

Packaging:

Pack of 2 strips of 10 tablets each.

Storage:

Store at room temperature, below 25°C.

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